Quantum Optical Coherence Microscopy for Bioimaging Applications

Quantum-optical coherence tomography (QOCT) is an optical sectioning modality based on the quantum interference of entangled photon pairs in well-known Hong-Ou-Mandel interferometer. Despite its promise, technique far from being competitive with current classical OCT devices due to long required acquisition times, derived low photon-pair emission rates. In this work, we, one hand, demonstrate a microscopy technique, full-field QOCT, which employs collinear Linnik interferometer designed overcome some limitations previous QOCT implementations, and, other test it representative samples, including glass layers manufactured transverse patterns and metal-coated biological specimens. our setup, while idler collected multimode fiber, signal detected by intensified charge-coupled device camera, leading reconstruction through single-axial sequence. Interestingly, setup permits concurrent trace acquisition, former greater counts latter benefit quantum-conferred advantages. We hope that results will represent significant step forward towards actual applicability e.g., clinical settings.